STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM12ADAM metallopeptidase domain 12. (876 aa)    
Predicted Functional Partners:
SH3PXD2A
SH3 and PX domains 2A.
    
 0.752
LGI1
Leucine rich glioma inactivated 1.
    
 0.583
SH3PXD2B
SH3 and PX domains 2B.
    
 0.529
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.527
TCERG1L
Transcription elongation regulator 1 like.
      
 0.506
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
  0.505
GRB2
Growth factor receptor bound protein 2.
    
 
 0.491
CDH3
Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins.
    
  0.486
LGI2
Leucine rich repeat LGI family member 2.
     
 0.476
PPP2R2D
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.475
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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