STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcgr2aIg-like domain-containing protein. (262 aa)    
Predicted Functional Partners:
INPPL1
Inositol polyphosphate phosphatase like 1.
    
 0.911
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
 0.886
H0V0F4_CAVPO
Uncharacterized protein.
   
 0.859
LOC100718571
Ig-like domain-containing protein.
   
  0.777
Fcgr4
Low affinity immunoglobulin gamma Fc region receptor IV; Receptor for the Fc region of immunoglobulin gamma. Also acts as a receptor for the Fc region of immunoglobulin epsilon (By similarity). Binds with intermediate affinity to both IgG2a and IgG2b (By similarity). Can bind to IgG2a and IgG2b monomers (By similarity). Does not display binding to IgG1 or IgG3 (By similarity). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (By similarity). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (By similarity) [...]
  
 
0.774
IGSF1
Immunoglobulin superfamily member 1.
   
 0.771
ZAP70
Tyrosine-protein kinase.
   
 0.752
SYK
Tyrosine-protein kinase.
   
 0.752
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.746
ENSCPOP00000022635
Uncharacterized protein.
   
 0.733
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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