STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (722 aa)    
Predicted Functional Partners:
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.953
SPATA5
Spermatogenesis associated 5.
   
 
 0.882
SPATA5L1
Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family.
   
 
 0.882
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
    
   0.873
NEMF
Nuclear export mediator factor.
   
 
 0.871
RPL3
Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
    
 
 0.700
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
    
 
 0.685
RPL32
Ribosomal protein L32.
    
   0.670
RPL5
Ribosomal_L18_c domain-containing protein.
    
   0.670
RPL38
Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
    
   0.670
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.