KBTBD12 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KBTBD12

Kelch repeat and BTB domain containing 12. (623 aa)

Predicted Functional Partners:

BBS9

0.686

CUL3

0.684

TTC8

0.663

MIB2

0.653

BBS7

0.647

Ubxn7

0.614

NBR1

0.611

KLHL23

0.586

ASB4

0.573

TMEM161B

0.571

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB4	KBTBD12	ENSCPOP00000012834	ENSCPOP00000004376	Ankyrin repeat and SOCS box containing 4.	Kelch repeat and BTB domain containing 12.	0.573
ASB4	Ubxn7	ENSCPOP00000012834	ENSCPOP00000009893	Ankyrin repeat and SOCS box containing 4.	UBX domain-containing protein 7.	0.554
BBS7	BBS9	ENSCPOP00000001110	ENSCPOP00000000840	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 9.	0.998
BBS7	KBTBD12	ENSCPOP00000001110	ENSCPOP00000004376	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch repeat and BTB domain containing 12.	0.647
BBS7	KLHL23	ENSCPOP00000001110	ENSCPOP00000006804	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch like family member 23.	0.647
BBS7	TTC8	ENSCPOP00000001110	ENSCPOP00000000619	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Tetratricopeptide repeat domain 8.	0.994
BBS9	BBS7	ENSCPOP00000000840	ENSCPOP00000001110	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.998
BBS9	KBTBD12	ENSCPOP00000000840	ENSCPOP00000004376	Bardet-Biedl syndrome 9.	Kelch repeat and BTB domain containing 12.	0.686
BBS9	KLHL23	ENSCPOP00000000840	ENSCPOP00000006804	Bardet-Biedl syndrome 9.	Kelch like family member 23.	0.686
BBS9	TTC8	ENSCPOP00000000840	ENSCPOP00000000619	Bardet-Biedl syndrome 9.	Tetratricopeptide repeat domain 8.	0.997
CUL3	KBTBD12	ENSCPOP00000005101	ENSCPOP00000004376	Cullin 3; Belongs to the cullin family.	Kelch repeat and BTB domain containing 12.	0.684
CUL3	KLHL23	ENSCPOP00000005101	ENSCPOP00000006804	Cullin 3; Belongs to the cullin family.	Kelch like family member 23.	0.682
CUL3	MIB2	ENSCPOP00000005101	ENSCPOP00000020436	Cullin 3; Belongs to the cullin family.	Mindbomb E3 ubiquitin protein ligase 2.	0.876
CUL3	NBR1	ENSCPOP00000005101	ENSCPOP00000021038	Cullin 3; Belongs to the cullin family.	NBR1 autophagy cargo receptor.	0.813
CUL3	Ubxn7	ENSCPOP00000005101	ENSCPOP00000009893	Cullin 3; Belongs to the cullin family.	UBX domain-containing protein 7.	0.996
KBTBD12	ASB4	ENSCPOP00000004376	ENSCPOP00000012834	Kelch repeat and BTB domain containing 12.	Ankyrin repeat and SOCS box containing 4.	0.573
KBTBD12	BBS7	ENSCPOP00000004376	ENSCPOP00000001110	Kelch repeat and BTB domain containing 12.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.647
KBTBD12	BBS9	ENSCPOP00000004376	ENSCPOP00000000840	Kelch repeat and BTB domain containing 12.	Bardet-Biedl syndrome 9.	0.686
KBTBD12	CUL3	ENSCPOP00000004376	ENSCPOP00000005101	Kelch repeat and BTB domain containing 12.	Cullin 3; Belongs to the cullin family.	0.684
KBTBD12	KLHL23	ENSCPOP00000004376	ENSCPOP00000006804	Kelch repeat and BTB domain containing 12.	Kelch like family member 23.	0.586