STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VWDEVon Willebrand factor D and EGF domains. (1695 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.772
NCSTN
Nicastrin.
    
 0.770
PSENEN
Presenilin enhancer, gamma-secretase subunit.
    
 0.728
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.648
PRMT6
Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
    
 
 0.648
NUMBL
NUMB like endocytic adaptor protein.
    
 0.642
NUMB
NUMB endocytic adaptor protein.
    
 0.642
DVL1
Dishevelled segment polarity protein 1.
    
  0.606
DVL2
Dishevelled segment polarity protein 2.
    
  0.606
DVL3
Dishevelled segment polarity protein 3.
    
  0.606
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.