STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cdk1Protein kinase domain-containing protein. (240 aa)    
Predicted Functional Partners:
CCNA2
Cyclin A2; Belongs to the cyclin family.
 
 
 0.993
PLK1
Serine/threonine-protein kinase PLK.
   
 0.970
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.966
CKS1B
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.963
LOC100720222
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.959
Ccnb1
annotation not available
   
 0.959
CDC20
Cell division cycle 20.
   
 0.957
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.949
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.947
Bub1b
Uncharacterized protein.
   
 0.946
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.