STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Casp7Uncharacterized protein; Belongs to the peptidase C14A family. (199 aa)    
Predicted Functional Partners:
XIAP
X-linked inhibitor of apoptosis.
   
 0.998
BIRC2
Baculoviral IAP repeat containing 2.
   
 0.971
BIRC3
Baculoviral IAP repeat containing 3.
   
 0.971
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.970
Parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.955
ENSCPOP00000024428
PARP-type domain-containing protein.
    
 0.955
APAF1
Apoptotic peptidase activating factor 1.
    
 0.949
PARP2
Poly [ADP-ribose] polymerase.
    
 0.947
PARP3
Poly [ADP-ribose] polymerase.
    
 0.942
BIRC7
Baculoviral IAP repeat containing 7.
   
 0.942
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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