STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL4Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa)    
Predicted Functional Partners:
METTL3
Methyltransferase like 3; Belongs to the MT-A70-like family.
      
 0.593
ALKBH4
AlkB homolog 4, lysine demethylase.
      
 0.592
WTAP
WT1 associated protein.
      
 0.591
METTL14
Methyltransferase like 14; Belongs to the MT-A70-like family.
      
 0.591
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
      
 0.583
ALKBH1
AlkB homolog 1, histone H2A dioxygenase.
   
  
 0.582
SMCHD1
Structural maintenance of chromosomes flexible hinge domain containing 1.
   
  
 0.572
VIRMA
Vir like m6A methyltransferase associated.
      
 0.561
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
      
 0.560
ALKBH2
AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase.
      
 0.508
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.