GAA protein (Cavia porcellus) - STRING interaction network

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GAA

Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)

Predicted Functional Partners:

GBA3

0.923

Ganc

0.922

GLA

0.919

SI

0.917

MGAM

0.914

HK1

0.912

HK2

0.912

HK3

0.912

HKDC1

0.912

LOC100724525

0.906

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAA	GBA3	ENSCPOP00000005480	ENSCPOP00000014554	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	0.923
GAA	GLA	ENSCPOP00000005480	ENSCPOP00000000485	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Alpha-galactosidase.	0.919
GAA	Ganc	ENSCPOP00000005480	ENSCPOP00000021022	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.922
GAA	HK1	ENSCPOP00000005480	ENSCPOP00000005421	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Hexokinase 1.	0.912
GAA	HK2	ENSCPOP00000005480	ENSCPOP00000008237	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Hexokinase 2.	0.912
GAA	HK3	ENSCPOP00000005480	ENSCPOP00000009290	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Hexokinase 3.	0.912
GAA	HKDC1	ENSCPOP00000005480	ENSCPOP00000026996	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Hexokinase domain containing 1.	0.912
GAA	LOC100724525	ENSCPOP00000005480	ENSCPOP00000023034	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Alpha-amylase.	0.906
GAA	MGAM	ENSCPOP00000005480	ENSCPOP00000010142	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Maltase-glucoamylase.	0.914
GAA	SI	ENSCPOP00000005480	ENSCPOP00000005303	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	Sucrase-isomaltase.	0.917
GBA3	GAA	ENSCPOP00000014554	ENSCPOP00000005480	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	0.923
GBA3	GLA	ENSCPOP00000014554	ENSCPOP00000000485	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Alpha-galactosidase.	0.759
GBA3	Ganc	ENSCPOP00000014554	ENSCPOP00000021022	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.925
GBA3	HK1	ENSCPOP00000014554	ENSCPOP00000005421	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Hexokinase 1.	0.410
GBA3	HK2	ENSCPOP00000014554	ENSCPOP00000008237	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Hexokinase 2.	0.410
GBA3	HK3	ENSCPOP00000014554	ENSCPOP00000009290	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Hexokinase 3.	0.410
GBA3	HKDC1	ENSCPOP00000014554	ENSCPOP00000026996	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Hexokinase domain containing 1.	0.410
GBA3	LOC100724525	ENSCPOP00000014554	ENSCPOP00000023034	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Alpha-amylase.	0.563
GBA3	MGAM	ENSCPOP00000014554	ENSCPOP00000010142	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Maltase-glucoamylase.	0.923
GBA3	SI	ENSCPOP00000014554	ENSCPOP00000005303	Cytosolic beta-glucosidase; Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (Probable). Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear (By similarity). Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear (By similarity). It can also hydrolyze a broad variety of dietary glycosides including phyt [...]	Sucrase-isomaltase.	0.923