STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKISKI proto-oncogene. (586 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
    
 0.996
SMAD2
Mothers against decapentaplegic homolog.
   
 0.993
SMAD3
Mothers against decapentaplegic homolog.
   
 0.969
NCOR1
Nuclear receptor corepressor 1.
   
 0.881
SMAD5
Mothers against decapentaplegic homolog.
   
 0.875
SMAD1
Mothers against decapentaplegic homolog.
   
 0.873
Smad9
Mothers against decapentaplegic homolog.
   
 0.873
NCOR2
Nuclear receptor corepressor 2.
   
 0.840
INTS8
Integrator complex subunit 8.
   
 0.828
SKIL
SKI like proto-oncogene.
    
 
0.776
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.