Tmprss2 protein (Cavia porcellus) - STRING interaction network

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Score

Tmprss2

Uncharacterized protein; Belongs to the peptidase S1 family. (488 aa)

Predicted Functional Partners:

TMPRSS4

0.855

ACE2

0.786

AR

0.766

FURIN

0.749

MET

0.738

MST1R

0.738

H0VWZ0_CAVPO

0.611

PTK7

0.606

F12

0.598

SERPING1

0.590

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	FURIN	ENSCPOP00000013557	ENSCPOP00000026315	Angiotensin-converting enzyme.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.666
ACE2	Tmprss2	ENSCPOP00000013557	ENSCPOP00000006362	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.786
AR	Tmprss2	ENSCPOP00000015421	ENSCPOP00000006362	Androgen receptor.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.766
F12	FURIN	ENSCPOP00000018858	ENSCPOP00000026315	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.476
F12	MET	ENSCPOP00000018858	ENSCPOP00000012177	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	MET proto-oncogene, receptor tyrosine kinase.	0.957
F12	MST1R	ENSCPOP00000018858	ENSCPOP00000028150	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	Macrophage stimulating 1 receptor.	0.953
F12	PTK7	ENSCPOP00000018858	ENSCPOP00000030004	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.973
F12	SERPING1	ENSCPOP00000018858	ENSCPOP00000024504	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	SERPIN domain-containing protein; Belongs to the serpin family.	0.832
F12	TMPRSS4	ENSCPOP00000018858	ENSCPOP00000005321	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.440
F12	Tmprss2	ENSCPOP00000018858	ENSCPOP00000006362	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	Uncharacterized protein; Belongs to the peptidase S1 family.	0.598
FURIN	ACE2	ENSCPOP00000026315	ENSCPOP00000013557	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Angiotensin-converting enzyme.	0.666
FURIN	F12	ENSCPOP00000026315	ENSCPOP00000018858	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	0.476
FURIN	TMPRSS4	ENSCPOP00000026315	ENSCPOP00000005321	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.590
FURIN	Tmprss2	ENSCPOP00000026315	ENSCPOP00000006362	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.749
H0VWZ0_CAVPO	MET	ENSCPOP00000015219	ENSCPOP00000012177	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	MET proto-oncogene, receptor tyrosine kinase.	0.738
H0VWZ0_CAVPO	MST1R	ENSCPOP00000015219	ENSCPOP00000028150	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.738
H0VWZ0_CAVPO	PTK7	ENSCPOP00000015219	ENSCPOP00000030004	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.606
H0VWZ0_CAVPO	SERPING1	ENSCPOP00000015219	ENSCPOP00000024504	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.480
H0VWZ0_CAVPO	Tmprss2	ENSCPOP00000015219	ENSCPOP00000006362	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.611
MET	F12	ENSCPOP00000012177	ENSCPOP00000018858	MET proto-oncogene, receptor tyrosine kinase.	Coagulation factor XIIa heavy chain; Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).	0.957