STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMER1APC membrane recruitment protein 1. (1127 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
    
 0.990
AXIN1
Axin 1.
    
 0.951
CTNNB1
Catenin beta 1.
    
 0.941
APC2
APC regulator of WNT signaling pathway 2.
    
 0.935
AXIN2
Axin 2.
    
 0.886
JUP
Junction plakoglobin.
    
 0.859
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
     
 0.843
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.824
KEAP1
Kelch like ECH associated protein 1.
    
 0.783
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.758
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.