STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD44CD44 molecule (Indian blood group). (660 aa)    
Predicted Functional Partners:
RDX
Radixin.
   
 
 0.962
ERBB2
Receptor protein-tyrosine kinase.
    
 0.955
EGFR
Receptor protein-tyrosine kinase.
    
 0.951
SELL
L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
   
 0.925
FN1
Fibronectin 1.
    
 0.922
MSN
Moesin.
   
 
 0.920
SPP1
Secreted phosphoprotein 1.
   
 0.917
CDC42
Cell division cycle 42.
   
 0.908
TIAM1
T cell lymphoma invasion and metastasis 1.
    
 0.905
COL1A1
Collagen type I alpha 1 chain.
    
 0.901
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.