node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG13 | IFNG | ENSCPOP00000019111 | ENSCPOP00000009919 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.750 |
ALG13 | IL15 | ENSCPOP00000019111 | ENSCPOP00000007401 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. | 0.944 |
ALG13 | IL2 | ENSCPOP00000019111 | ENSCPOP00000007430 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.790 |
ALG13 | IL2RA | ENSCPOP00000019111 | ENSCPOP00000005118 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin 2 receptor subunit alpha. | 0.906 |
ALG13 | IL2RB | ENSCPOP00000019111 | ENSCPOP00000025841 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin 2 receptor subunit beta. | 0.972 |
ALG13 | IL7 | ENSCPOP00000019111 | ENSCPOP00000029913 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin 7. | 0.855 |
ALG13 | IL7R | ENSCPOP00000019111 | ENSCPOP00000027822 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin 7 receptor. | 0.831 |
ALG13 | Il15ra | ENSCPOP00000019111 | ENSCPOP00000002274 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin-15 receptor alpha chain. | 0.926 |
ALG13 | Il4 | ENSCPOP00000019111 | ENSCPOP00000031420 | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | Interleukin-4. | 0.797 |
IFNG | ALG13 | ENSCPOP00000009919 | ENSCPOP00000019111 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | 0.750 |
IFNG | IL15 | ENSCPOP00000009919 | ENSCPOP00000007401 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. | 0.947 |
IFNG | IL2 | ENSCPOP00000009919 | ENSCPOP00000007430 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.914 |
IFNG | IL2RA | ENSCPOP00000009919 | ENSCPOP00000005118 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 2 receptor subunit alpha. | 0.927 |
IFNG | IL2RB | ENSCPOP00000009919 | ENSCPOP00000025841 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 2 receptor subunit beta. | 0.886 |
IFNG | IL7 | ENSCPOP00000009919 | ENSCPOP00000029913 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 7. | 0.776 |
IFNG | IL7R | ENSCPOP00000009919 | ENSCPOP00000027822 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 7 receptor. | 0.879 |
IFNG | Il15ra | ENSCPOP00000009919 | ENSCPOP00000002274 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-15 receptor alpha chain. | 0.821 |
IFNG | Il2rg | ENSCPOP00000009919 | ENSCPOP00000029284 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Fibronectin type-III domain-containing protein. | 0.851 |
IFNG | Il4 | ENSCPOP00000009919 | ENSCPOP00000031420 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-4. | 0.835 |
IL15 | ALG13 | ENSCPOP00000007401 | ENSCPOP00000019111 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. | ALG13 UDP-N-acetylglucosaminyltransferase subunit. | 0.944 |