STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CtsdPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (407 aa)    
Predicted Functional Partners:
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.969
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.957
BCL2
BCL2 apoptosis regulator.
     
 0.919
BCL2L1
BCL2 like 1.
     
 0.913
H0W5F0_CAVPO
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
  0.910
CTSV
Cathepsin V; Belongs to the peptidase C1 family.
   
 0.796
XIAP
X-linked inhibitor of apoptosis.
    
  0.785
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.780
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.775
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
   
 0.768
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.