STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.999
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.998
ITSN1
Intersectin 1.
    
 0.979
IQGAP1
IQ motif containing GTPase activating protein 1.
   
 0.962
TIAM1
T cell lymphoma invasion and metastasis 1.
    
 0.961
NCF2
Neutrophil cytosolic factor 2.
   
 0.958
BAIAP2
BAI1 associated protein 2.
   
 0.951
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.950
PAK1
Non-specific serine/threonine protein kinase.
    
 0.947
NCF4
Neutrophil cytosolic factor 4.
   
 0.946
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.