GATA3 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GATA3

GATA binding protein 3. (443 aa)

Predicted Functional Partners:

TBX21

0.974

TAL1

0.905

ESR1

0.895

FOXA2

0.875

EP300

0.858

STAT6

0.819

ZFPM1

0.810

FOXP3

0.792

LMO2

0.791

USP21

0.787

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	ESR1	ENSCPOP00000004894	ENSCPOP00000007475	E1A binding protein p300.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.985
EP300	FOXA2	ENSCPOP00000004894	ENSCPOP00000026387	E1A binding protein p300.	Forkhead box A2.	0.765
EP300	FOXP3	ENSCPOP00000004894	ENSCPOP00000006266	E1A binding protein p300.	Forkhead box P3.	0.589
EP300	GATA3	ENSCPOP00000004894	ENSCPOP00000007724	E1A binding protein p300.	GATA binding protein 3.	0.858
EP300	STAT6	ENSCPOP00000004894	ENSCPOP00000011650	E1A binding protein p300.	Signal transducer and activator of transcription.	0.963
EP300	TAL1	ENSCPOP00000004894	ENSCPOP00000003215	E1A binding protein p300.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.687
EP300	ZFPM1	ENSCPOP00000004894	ENSCPOP00000014485	E1A binding protein p300.	Zinc finger protein, FOG family member 1.	0.666
ESR1	EP300	ENSCPOP00000007475	ENSCPOP00000004894	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	E1A binding protein p300.	0.985
ESR1	FOXA2	ENSCPOP00000007475	ENSCPOP00000026387	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Forkhead box A2.	0.885
ESR1	GATA3	ENSCPOP00000007475	ENSCPOP00000007724	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	GATA binding protein 3.	0.895
ESR1	STAT6	ENSCPOP00000007475	ENSCPOP00000011650	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Signal transducer and activator of transcription.	0.425
FOXA2	EP300	ENSCPOP00000026387	ENSCPOP00000004894	Forkhead box A2.	E1A binding protein p300.	0.765
FOXA2	ESR1	ENSCPOP00000026387	ENSCPOP00000007475	Forkhead box A2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.885
FOXA2	GATA3	ENSCPOP00000026387	ENSCPOP00000007724	Forkhead box A2.	GATA binding protein 3.	0.875
FOXA2	STAT6	ENSCPOP00000026387	ENSCPOP00000011650	Forkhead box A2.	Signal transducer and activator of transcription.	0.435
FOXA2	TBX21	ENSCPOP00000026387	ENSCPOP00000017990	Forkhead box A2.	T-box transcription factor 21.	0.449
FOXP3	EP300	ENSCPOP00000006266	ENSCPOP00000004894	Forkhead box P3.	E1A binding protein p300.	0.589
FOXP3	GATA3	ENSCPOP00000006266	ENSCPOP00000007724	Forkhead box P3.	GATA binding protein 3.	0.792
FOXP3	STAT6	ENSCPOP00000006266	ENSCPOP00000011650	Forkhead box P3.	Signal transducer and activator of transcription.	0.605
FOXP3	TBX21	ENSCPOP00000006266	ENSCPOP00000017990	Forkhead box P3.	T-box transcription factor 21.	0.625