STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIMP2Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. (220 aa)    
Predicted Functional Partners:
MMP2
Matrix metallopeptidase 2.
   
 0.996
MMP14
Matrix metallopeptidase 14.
    
 0.989
MMP13
Matrix metallopeptidase 13.
   
 0.968
MMP15
Matrix metallopeptidase 15.
    
 0.960
MMP9
Matrix metallopeptidase 9.
   
 0.953
MMP3
Matrix metallopeptidase 3.
   
 0.917
MMP1
Matrix metallopeptidase 1.
   
 0.911
H0VKC6_CAVPO
Fibronectin type-II domain-containing protein.
   
 0.903
MMP16
Matrix metallopeptidase 16.
    
 0.886
MMP8
Matrix metallopeptidase 8.
   
 0.881
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.