STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACANAggrecan. (2119 aa)    
Predicted Functional Partners:
TNR
Tenascin R.
   
 0.981
COMP
Cartilage oligomeric matrix protein.
   
 0.932
TNC
Tenascin C.
   
 0.928
HAPLN1
Hyaluronan and proteoglycan link protein 1.
   
0.914
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
    
   0.881
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5.
     
 0.879
FMOD
Fibromodulin.
     
 0.868
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4.
     
 0.867
DCN
Decorin; May affect the rate of fibrils formation.
    
 0.858
BGN
Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
     
 0.844
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.