STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCE1Phosphoinositide phospholipase C. (2282 aa)    
Predicted Functional Partners:
NRAS
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
    
 0.974
HRAS
HRas proto-oncogene, GTPase.
    
 0.974
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.961
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.943
RRAS2
RAS related 2.
   
 0.940
RRAS
RAS related.
   
 0.940
RHOA
Ras homolog family member A.
    
 0.938
INPP5J
Inositol polyphosphate-5-phosphatase J.
     
 0.937
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
    
 0.928
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
 0.928
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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