STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (256 aa)    
Predicted Functional Partners:
ACTG2
Actin gamma 2, smooth muscle.
   
 0.901
WDR90
WD repeat domain 90.
    
 
 0.896
MYH11
Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.895
TAGLN
Transgelin; Belongs to the calponin family.
  
 
0.836
ACTA2
Actin alpha 2, smooth muscle.
   
 0.760
MRGPRF
MAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family.
   
    0.757
SMTN
Smoothelin.
   
  
 0.756
CALML4
Calmodulin like 4.
   
 0.739
CALB2
Calbindin 2.
   
 0.737
ENKUR
Enkurin, TRPC channel interacting protein.
   
 
 0.712
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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