ADAM10 protein (Cavia porcellus) - STRING interaction network

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Score

ADAM10

ADAM metallopeptidase domain 10. (679 aa)

Predicted Functional Partners:

ADAM17

0.943

TSPAN33

0.942

APP

0.823

EFNA2

0.822

HBEGF

0.768

NOTCH1

0.762

DLL1

0.760

NCSTN

0.759

TSPAN14

0.757

NOTCH2

0.732

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	ADAM17	ENSCPOP00000009443	ENSCPOP00000010172	ADAM metallopeptidase domain 10.	ADAM metallopeptidase domain 17.	0.943
ADAM10	APP	ENSCPOP00000009443	ENSCPOP00000020780	ADAM metallopeptidase domain 10.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.823
ADAM10	DLL1	ENSCPOP00000009443	ENSCPOP00000017174	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.760
ADAM10	EFNA2	ENSCPOP00000009443	ENSCPOP00000017648	ADAM metallopeptidase domain 10.	Ephrin A2; Belongs to the ephrin family.	0.822
ADAM10	HBEGF	ENSCPOP00000009443	ENSCPOP00000009291	ADAM metallopeptidase domain 10.	Heparin binding EGF like growth factor.	0.768
ADAM10	NCSTN	ENSCPOP00000009443	ENSCPOP00000013448	ADAM metallopeptidase domain 10.	Nicastrin.	0.759
ADAM10	NOTCH1	ENSCPOP00000009443	ENSCPOP00000011665	ADAM metallopeptidase domain 10.	Notch receptor 1.	0.762
ADAM10	NOTCH2	ENSCPOP00000009443	ENSCPOP00000014192	ADAM metallopeptidase domain 10.	Notch receptor 2.	0.732
ADAM10	TSPAN14	ENSCPOP00000009443	ENSCPOP00000008879	ADAM metallopeptidase domain 10.	Tetraspanin.	0.757
ADAM10	TSPAN33	ENSCPOP00000009443	ENSCPOP00000015562	ADAM metallopeptidase domain 10.	Tetraspanin.	0.942
ADAM17	ADAM10	ENSCPOP00000010172	ENSCPOP00000009443	ADAM metallopeptidase domain 17.	ADAM metallopeptidase domain 10.	0.943
ADAM17	APP	ENSCPOP00000010172	ENSCPOP00000020780	ADAM metallopeptidase domain 17.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.601
ADAM17	DLL1	ENSCPOP00000010172	ENSCPOP00000017174	ADAM metallopeptidase domain 17.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.516
ADAM17	HBEGF	ENSCPOP00000010172	ENSCPOP00000009291	ADAM metallopeptidase domain 17.	Heparin binding EGF like growth factor.	0.826
ADAM17	NCSTN	ENSCPOP00000010172	ENSCPOP00000013448	ADAM metallopeptidase domain 17.	Nicastrin.	0.686
ADAM17	NOTCH1	ENSCPOP00000010172	ENSCPOP00000011665	ADAM metallopeptidase domain 17.	Notch receptor 1.	0.941
ADAM17	NOTCH2	ENSCPOP00000010172	ENSCPOP00000014192	ADAM metallopeptidase domain 17.	Notch receptor 2.	0.927
APP	ADAM10	ENSCPOP00000020780	ENSCPOP00000009443	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	ADAM metallopeptidase domain 10.	0.823
APP	ADAM17	ENSCPOP00000020780	ENSCPOP00000010172	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	ADAM metallopeptidase domain 17.	0.601
APP	NCSTN	ENSCPOP00000020780	ENSCPOP00000013448	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Nicastrin.	0.987