STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX6Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping. (474 aa)    
Predicted Functional Partners:
DCP2
Decapping mRNA 2.
   
 0.999
EDC3
Enhancer of mRNA decapping 3.
   
 0.999
LSM7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
 0.998
LSM1
U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
    
 0.998
PATL1
PAT1 homolog 1, processing body mRNA decay factor.
   
 0.997
CNOT1
CCR4-NOT transcription complex subunit 1.
   
 0.996
EDC4
Enhancer of mRNA decapping 4.
    
 0.995
CNOT4
CCR4-NOT transcription complex subunit 4.
    
 0.994
EIF4ENIF1
Eukaryotic translation initiation factor 4E nuclear import factor 1.
  
 0.993
DCP1B
Decapping mRNA 1B.
   
 0.989
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.