STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D4TBC1 domain family member 4. (1302 aa)    
Predicted Functional Partners:
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.971
AKT3
AKT serine/threonine kinase 3.
    
 0.931
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.887
RAB14
RAB14, member RAS oncogene family.
    
 0.879
LNPEP
Leucyl and cystinyl aminopeptidase.
     
 0.772
RAB11A
Uncharacterized protein.
    
 0.767
RAB11B
RAB11B, member RAS oncogene family.
    
 0.767
RAB2A
RAB2A, member RAS oncogene family.
    
 0.764
RAB10
RAB10, member RAS oncogene family.
    
 0.763
RAB8A
RAB8A, member RAS oncogene family.
    
 0.742
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.