STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP12Poly(ADP-ribose) polymerase family member 12. (603 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 
 0.730
PARP4
Poly [ADP-ribose] polymerase.
    
 
 0.675
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.572
PARP16
Poly [ADP-ribose] polymerase.
      
 0.555
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.554
FREM3
FRAS1 related extracellular matrix 3.
      
 0.554
IFI35
Interferon induced protein 35.
   
    0.545
DHX58
DExH-box helicase 58.
   
 
 0.537
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.533
DDX58
DExD/H-box helicase 58.
   
 
 0.526
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.