STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1198 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.840
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.744
STRN
Striatin.
    
 
 0.669
MINK1
Misshapen like kinase 1.
  
0.631
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
0.620
MAP3K20
Mitogen-activated protein kinase kinase kinase 20.
    
0.616
NCK1
Cytoplasmic protein.
    
 
 0.606
NCK2
Cytoplasmic protein.
    
 
 0.600
STRN3
Striatin 3.
    
 
 0.591
STRN4
Striatin 4.
    
 
 0.552
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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