STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKP4Plakophilin 4. (1195 aa)    
Predicted Functional Partners:
JUP
Junction plakoglobin.
    
 0.887
CTNNB1
Catenin beta 1.
    
 0.831
CTNNA2
Catenin alpha 2.
   
 0.794
CTNNA3
Catenin alpha 3.
   
 0.794
CTNNA1
Catenin alpha 1.
   
 0.794
ENSCPOP00000030889
Uncharacterized protein.
   
 0.794
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.789
CDH2
Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.774
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.774
ERBIN
Erbb2 interacting protein.
    
 
 0.773
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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