STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAVSMitochondrial antiviral signaling protein. (533 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
    
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
IFIH1
Interferon induced with helicase C domain 1.
    
 0.999
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.998
TBK1
TANK binding kinase 1.
    
 0.997
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.996
STING1
Transmembrane protein 173.
    
 0.993
NLRX1
NLR family member X1.
    
 0.986
IRF3
Interferon regulatory factor 3.
    
 0.985
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.