STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMA1Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. (247 aa)    
Predicted Functional Partners:
CPA3
Carboxypeptidase A3.
   
 
 0.946
FYN
Tyrosine-protein kinase.
   
 0.905
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.824
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
     
 0.785
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.738
MST1R
Macrophage stimulating 1 receptor.
    
  0.738
ENSCPOP00000028372
Peptidase S1 domain-containing protein.
  
 
0.692
H0VWZ0_CAVPO
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.681
PTK6
Tyrosine-protein kinase.
   
 0.627
SRMS
Tyrosine-protein kinase.
   
 0.627
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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