STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)    
Predicted Functional Partners:
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
  
 
0.969
CHRNA6
Cholinergic receptor nicotinic alpha 6 subunit.
  
  
0.944
JAK2
Tyrosine-protein kinase.
    
 0.915
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.873
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
  
 
0.850
CHRNB4
Cholinergic receptor nicotinic beta 4 subunit.
  
 
0.847
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
  
 
0.818
SLURP1
Secreted LY6/PLAUR domain containing 1.
     
 0.775
Chrna7
Uncharacterized protein.
  
0.769
CHRNB3
Cholinergic receptor nicotinic beta 3 subunit.
  
0.731
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.