STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pla2g7Platelet-activating factor acetylhydrolase; Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids; Belongs to the AB hydrolase superfamily. Lipase family (436 aa)    
Predicted Functional Partners:
LPCAT2
Lysophosphatidylcholine acyltransferase 2
   
 
 0.980
LPCAT1
Lysophosphatidylcholine acyltransferase 1
   
 
 0.961
LPCAT4
Lysophosphatidylcholine acyltransferase 4
   
 
 0.951
PAFAH1B3
Platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
     
 0.949
Pla2g1b
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family
     
 0.944
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family
   
 
 0.938
PAFAH2
Platelet-activating factor acetylhydrolase 2, 40kDa
     
0.936
PLA2G4A
Phospholipase A2, group IVA (cytosolic, calcium-dependent)
     
 0.934
PAFAH1B2
Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
     
 0.929
PLA2G10
Phospholipase a(2); Phospholipase A2, group X
     
 0.916
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, Cavia cobya, domestic guinea pig, guinea pig
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