INSR protein (Cavia porcellus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

INSR

Tyrosine-protein kinase receptor. (1371 aa)

Predicted Functional Partners:

PTPN1

0.998

INS

0.998

IGF1R

0.994

GRB10

0.991

GRB14

0.990

IRS1

0.990

PIK3R1

0.990

SH2B2

0.980

SHC1

0.977

PTPN11

0.972

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB10	IGF1R	ENSCPOP00000008282	ENSCPOP00000004859	Growth factor receptor bound protein 10.	Tyrosine-protein kinase receptor.	0.994
GRB10	INS	ENSCPOP00000008282	ENSCPOP00000026989	Growth factor receptor bound protein 10.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.745
GRB10	INSR	ENSCPOP00000008282	ENSCPOP00000011692	Growth factor receptor bound protein 10.	Tyrosine-protein kinase receptor.	0.991
GRB10	IRS1	ENSCPOP00000008282	ENSCPOP00000004880	Growth factor receptor bound protein 10.	Insulin receptor substrate 1.	0.676
GRB10	PIK3R1	ENSCPOP00000008282	ENSCPOP00000007043	Growth factor receptor bound protein 10.	Phosphoinositide-3-kinase regulatory subunit 1.	0.848
GRB10	PTPN1	ENSCPOP00000008282	ENSCPOP00000022412	Growth factor receptor bound protein 10.	Tyrosine-protein phosphatase non-receptor type.	0.502
GRB10	PTPN11	ENSCPOP00000008282	ENSCPOP00000012179	Growth factor receptor bound protein 10.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.500
GRB10	SHC1	ENSCPOP00000008282	ENSCPOP00000018761	Growth factor receptor bound protein 10.	SHC adaptor protein 1.	0.592
GRB14	IGF1R	ENSCPOP00000000761	ENSCPOP00000004859	Growth factor receptor bound protein 14.	Tyrosine-protein kinase receptor.	0.825
GRB14	INS	ENSCPOP00000000761	ENSCPOP00000026989	Growth factor receptor bound protein 14.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.618
GRB14	INSR	ENSCPOP00000000761	ENSCPOP00000011692	Growth factor receptor bound protein 14.	Tyrosine-protein kinase receptor.	0.990
GRB14	IRS1	ENSCPOP00000000761	ENSCPOP00000004880	Growth factor receptor bound protein 14.	Insulin receptor substrate 1.	0.561
GRB14	PIK3R1	ENSCPOP00000000761	ENSCPOP00000007043	Growth factor receptor bound protein 14.	Phosphoinositide-3-kinase regulatory subunit 1.	0.686
GRB14	PTPN1	ENSCPOP00000000761	ENSCPOP00000022412	Growth factor receptor bound protein 14.	Tyrosine-protein phosphatase non-receptor type.	0.509
GRB14	PTPN11	ENSCPOP00000000761	ENSCPOP00000012179	Growth factor receptor bound protein 14.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.500
GRB14	SHC1	ENSCPOP00000000761	ENSCPOP00000018761	Growth factor receptor bound protein 14.	SHC adaptor protein 1.	0.631
IGF1R	GRB10	ENSCPOP00000004859	ENSCPOP00000008282	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 10.	0.994
IGF1R	GRB14	ENSCPOP00000004859	ENSCPOP00000000761	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 14.	0.825
IGF1R	INS	ENSCPOP00000004859	ENSCPOP00000026989	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
IGF1R	INSR	ENSCPOP00000004859	ENSCPOP00000011692	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.994