Etv2 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Etv2

ETS domain-containing protein. (153 aa)

Predicted Functional Partners:

SRF

0.626

RUNX1

0.614

RUNX2

0.614

RUNX3

0.614

FOXC2

0.560

GATA2

0.479

MAPK8

0.478

MAPK9

0.478

MAPK10

0.478

PAX5

0.453

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Etv2	FOXC2	ENSCPOP00000011891	ENSCPOP00000020070	ETS domain-containing protein.	Forkhead box C2.	0.560
Etv2	GATA2	ENSCPOP00000011891	ENSCPOP00000008799	ETS domain-containing protein.	GATA binding protein 2.	0.479
Etv2	MAPK10	ENSCPOP00000011891	ENSCPOP00000033007	ETS domain-containing protein.	Mitogen-activated protein kinase 10.	0.478
Etv2	MAPK8	ENSCPOP00000011891	ENSCPOP00000024414	ETS domain-containing protein.	Mitogen-activated protein kinase.	0.478
Etv2	MAPK9	ENSCPOP00000011891	ENSCPOP00000025066	ETS domain-containing protein.	Mitogen-activated protein kinase.	0.478
Etv2	PAX5	ENSCPOP00000011891	ENSCPOP00000008962	ETS domain-containing protein.	Paired box 5.	0.453
Etv2	RUNX1	ENSCPOP00000011891	ENSCPOP00000021315	ETS domain-containing protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.614
Etv2	RUNX2	ENSCPOP00000011891	ENSCPOP00000026571	ETS domain-containing protein.	RUNX family transcription factor 2.	0.614
Etv2	RUNX3	ENSCPOP00000011891	ENSCPOP00000030407	ETS domain-containing protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.614
Etv2	SRF	ENSCPOP00000011891	ENSCPOP00000015471	ETS domain-containing protein.	Serum response factor.	0.626
FOXC2	Etv2	ENSCPOP00000020070	ENSCPOP00000011891	Forkhead box C2.	ETS domain-containing protein.	0.560
FOXC2	GATA2	ENSCPOP00000020070	ENSCPOP00000008799	Forkhead box C2.	GATA binding protein 2.	0.673
FOXC2	SRF	ENSCPOP00000020070	ENSCPOP00000015471	Forkhead box C2.	Serum response factor.	0.483
GATA2	Etv2	ENSCPOP00000008799	ENSCPOP00000011891	GATA binding protein 2.	ETS domain-containing protein.	0.479
GATA2	FOXC2	ENSCPOP00000008799	ENSCPOP00000020070	GATA binding protein 2.	Forkhead box C2.	0.673
GATA2	RUNX1	ENSCPOP00000008799	ENSCPOP00000021315	GATA binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.780
GATA2	RUNX2	ENSCPOP00000008799	ENSCPOP00000026571	GATA binding protein 2.	RUNX family transcription factor 2.	0.733
GATA2	RUNX3	ENSCPOP00000008799	ENSCPOP00000030407	GATA binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.733
GATA2	SRF	ENSCPOP00000008799	ENSCPOP00000015471	GATA binding protein 2.	Serum response factor.	0.751
MAPK10	Etv2	ENSCPOP00000033007	ENSCPOP00000011891	Mitogen-activated protein kinase 10.	ETS domain-containing protein.	0.478