STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (798 aa)    
Predicted Functional Partners:
RRM2
Ribonucleotide reductase regulatory subunit M2.
  
 0.999
RRM2B
Ribonucleotide reductase regulatory TP53 inducible subunit M2B.
  
 0.999
GLRX
Glutaredoxin.
  
 0.982
GLRX2
Glutaredoxin 2.
  
 0.981
TYMS
Thymidylate synthetase.
  
  
 0.969
CMPK2
Cytidine/uridine monophosphate kinase 2.
  
 
 0.966
DTYMK
Deoxythymidylate kinase.
  
 
 0.966
MCM5
DNA helicase; Belongs to the MCM family.
   
 
 0.964
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.962
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.961
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.