STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIK2Salt inducible kinase 2. (883 aa)    
Predicted Functional Partners:
CRTC2
CREB regulated transcription coactivator 2.
    
 0.980
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 
0.922
Prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 
0.922
CRTC3
CREB regulated transcription coactivator 3.
    
 0.876
PRKG1
cGMP-dependent protein kinase.
   
 
 
0.683
KSR2
Kinase suppressor of ras 2.
    
 
0.630
KSR1
Kinase suppressor of ras 1.
    
 
0.630
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.616
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
 0.616
H0VBD1_CAVPO
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.579
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.