Brca1 protein (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Experiments

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[Homology]

Score

Brca1

Uncharacterized protein. (79 aa)

Predicted Functional Partners:

RBBP8

0.999

BARD1

0.999

BRIP1

0.999

ABRAXAS1

0.998

TOPBP1

0.998

PALB2

0.997

Babam1

0.997

UIMC1

0.997

MRE11

0.997

BRCA2

0.996

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABRAXAS1	BARD1	ENSCPOP00000001244	ENSCPOP00000010340	Abraxas 1, BRCA1 A complex subunit.	BRCA1 associated RING domain 1.	0.998
ABRAXAS1	Babam1	ENSCPOP00000001244	ENSCPOP00000006248	Abraxas 1, BRCA1 A complex subunit.	Uncharacterized protein.	0.999
ABRAXAS1	Brca1	ENSCPOP00000001244	ENSCPOP00000012252	Abraxas 1, BRCA1 A complex subunit.	Uncharacterized protein.	0.998
ABRAXAS1	MRE11	ENSCPOP00000001244	ENSCPOP00000013122	Abraxas 1, BRCA1 A complex subunit.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.706
ABRAXAS1	RBBP8	ENSCPOP00000001244	ENSCPOP00000006941	Abraxas 1, BRCA1 A complex subunit.	RB binding protein 8, endonuclease.	0.617
ABRAXAS1	UIMC1	ENSCPOP00000001244	ENSCPOP00000009303	Abraxas 1, BRCA1 A complex subunit.	Ubiquitin interaction motif containing 1.	0.998
BARD1	ABRAXAS1	ENSCPOP00000010340	ENSCPOP00000001244	BRCA1 associated RING domain 1.	Abraxas 1, BRCA1 A complex subunit.	0.998
BARD1	BRCA2	ENSCPOP00000010340	ENSCPOP00000004635	BRCA1 associated RING domain 1.	BRCA2 DNA repair associated.	0.990
BARD1	BRIP1	ENSCPOP00000010340	ENSCPOP00000010475	BRCA1 associated RING domain 1.	BRCA1 interacting protein C-terminal helicase 1.	0.997
BARD1	Babam1	ENSCPOP00000010340	ENSCPOP00000006248	BRCA1 associated RING domain 1.	Uncharacterized protein.	0.985
BARD1	Brca1	ENSCPOP00000010340	ENSCPOP00000012252	BRCA1 associated RING domain 1.	Uncharacterized protein.	0.999
BARD1	MRE11	ENSCPOP00000010340	ENSCPOP00000013122	BRCA1 associated RING domain 1.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
BARD1	PALB2	ENSCPOP00000010340	ENSCPOP00000006213	BRCA1 associated RING domain 1.	Partner and localizer of BRCA2.	0.983
BARD1	RBBP8	ENSCPOP00000010340	ENSCPOP00000006941	BRCA1 associated RING domain 1.	RB binding protein 8, endonuclease.	0.998
BARD1	TOPBP1	ENSCPOP00000010340	ENSCPOP00000027324	BRCA1 associated RING domain 1.	DNA topoisomerase II binding protein 1.	0.997
BARD1	UIMC1	ENSCPOP00000010340	ENSCPOP00000009303	BRCA1 associated RING domain 1.	Ubiquitin interaction motif containing 1.	0.960
BRCA2	BARD1	ENSCPOP00000004635	ENSCPOP00000010340	BRCA2 DNA repair associated.	BRCA1 associated RING domain 1.	0.990
BRCA2	BRIP1	ENSCPOP00000004635	ENSCPOP00000010475	BRCA2 DNA repair associated.	BRCA1 interacting protein C-terminal helicase 1.	0.936
BRCA2	Brca1	ENSCPOP00000004635	ENSCPOP00000012252	BRCA2 DNA repair associated.	Uncharacterized protein.	0.996
BRCA2	MRE11	ENSCPOP00000004635	ENSCPOP00000013122	BRCA2 DNA repair associated.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.844