STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHB1Pleckstrin homology domain containing B1. (243 aa)    
Predicted Functional Partners:
SYNGR4
Synaptogyrin.
      
 0.554
SHANK1
SH3 and multiple ankyrin repeat domains 1.
      
 0.552
AP1M2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
      
 0.518
BOLA1
BolA family member 1; Belongs to the BolA/IbaG family.
      
 0.467
ICA1
Islet cell autoantigen 1.
      
 0.451
MXD3
MAX dimerization protein 3.
      
 0.429
CCKBR
Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.420
NRIP1
Nuclear receptor interacting protein 1.
      
 0.412
SLC25A13
Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.405
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.