STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARSKArylsulfatase family member K. (544 aa)    
Predicted Functional Partners:
ARSI
Arylsulfatase family member I.
  
  
 0.867
IDUA
Iduronidase alpha-L-.
     
 0.787
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
  
 0.786
ARSG
Arylsulfatase G.
  
  
 0.780
ARSB
Arylsulfatase B.
  
  
 0.763
ARSJ
Arylsulfatase family member J.
  
  
 0.762
Sumf2
FGE-sulfatase domain-containing protein.
  
 
 0.724
SUMF1
Sulfatase modifying factor 1.
  
 
 0.718
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
  
  
0.698
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.688
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.