STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLPPATP-dependent Clp protease proteolytic subunit. (272 aa)    
Predicted Functional Partners:
CLPX
Caseinolytic mitochondrial matrix peptidase chaperone subunit.
 0.999
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.998
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8.
  
 
 0.904
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
  
 
 0.900
TUFM
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.893
LOC100715002
Uncharacterized protein; Belongs to the GroES chaperonin family.
 
 
 0.872
MRPS11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.857
PDF
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
  
  
 0.856
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.853
NDUFS7
NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family.
  
 
 0.853
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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