IQGAP1 protein (Cavia porcellus) - STRING interaction network

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Score

IQGAP1

IQ motif containing GTPase activating protein 1. (1603 aa)

Predicted Functional Partners:

CDC42

0.998

CTNNB1

0.981

ITSN2

0.980

RAC2

0.965

RAC1

0.962

ACTB

0.945

ACTG1

0.945

MAPK1

0.941

MAPK3

0.941

IQGAP3

0.916

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSCPOP00000022236	ENSCPOP00000030661	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Actin gamma 1.	0.909
ACTB	CDC42	ENSCPOP00000022236	ENSCPOP00000031577	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cell division cycle 42.	0.940
ACTB	CTNNB1	ENSCPOP00000022236	ENSCPOP00000032871	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Catenin beta 1.	0.452
ACTB	IQGAP1	ENSCPOP00000022236	ENSCPOP00000012599	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	IQ motif containing GTPase activating protein 1.	0.945
ACTB	IQGAP3	ENSCPOP00000022236	ENSCPOP00000024468	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	IQ motif containing GTPase activating protein 3.	0.608
ACTB	ITSN2	ENSCPOP00000022236	ENSCPOP00000012160	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Intersectin 2.	0.977
ACTB	RAC1	ENSCPOP00000022236	ENSCPOP00000022339	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Ras-related C3 botulinum toxin substrate 1.	0.415
ACTB	RAC2	ENSCPOP00000022236	ENSCPOP00000014775	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).	0.415
ACTG1	ACTB	ENSCPOP00000030661	ENSCPOP00000022236	Actin gamma 1.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.909
ACTG1	CDC42	ENSCPOP00000030661	ENSCPOP00000031577	Actin gamma 1.	Cell division cycle 42.	0.931
ACTG1	CTNNB1	ENSCPOP00000030661	ENSCPOP00000032871	Actin gamma 1.	Catenin beta 1.	0.452
ACTG1	IQGAP1	ENSCPOP00000030661	ENSCPOP00000012599	Actin gamma 1.	IQ motif containing GTPase activating protein 1.	0.945
ACTG1	IQGAP3	ENSCPOP00000030661	ENSCPOP00000024468	Actin gamma 1.	IQ motif containing GTPase activating protein 3.	0.608
ACTG1	ITSN2	ENSCPOP00000030661	ENSCPOP00000012160	Actin gamma 1.	Intersectin 2.	0.977
ACTG1	RAC1	ENSCPOP00000030661	ENSCPOP00000022339	Actin gamma 1.	Ras-related C3 botulinum toxin substrate 1.	0.494
ACTG1	RAC2	ENSCPOP00000030661	ENSCPOP00000014775	Actin gamma 1.	Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).	0.415
CDC42	ACTB	ENSCPOP00000031577	ENSCPOP00000022236	Cell division cycle 42.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.940
CDC42	ACTG1	ENSCPOP00000031577	ENSCPOP00000030661	Cell division cycle 42.	Actin gamma 1.	0.931
CDC42	CTNNB1	ENSCPOP00000031577	ENSCPOP00000032871	Cell division cycle 42.	Catenin beta 1.	0.787
CDC42	IQGAP1	ENSCPOP00000031577	ENSCPOP00000012599	Cell division cycle 42.	IQ motif containing GTPase activating protein 1.	0.998