STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP4Poly [ADP-ribose] polymerase. (1702 aa)    
Predicted Functional Partners:
MVP
Major vault protein.
    
 
 0.955
Casp7
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.931
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.931
Casp3
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
    
 0.882
PARP3
Poly [ADP-ribose] polymerase.
     
0.871
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.865
TEP1
Telomerase associated protein 1.
    
 
 0.843
PARP2
Poly [ADP-ribose] polymerase.
     
0.830
CENPU
Centromere protein U.
    
 0.746
Parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
     
0.742
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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