STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTR1AActin related protein 1A. (376 aa)    
Predicted Functional Partners:
DCTN2
Dynactin subunit 2.
   
 0.999
ACTR10
Actin related protein 10; Belongs to the actin family.
   
0.998
DCTN6
Dynactin subunit 6.
    
 0.997
DCTN4
Dynactin subunit 4.
   
 0.997
DCTN5
Dynactin subunit 5.
 
 
 0.997
Dctn1
CAP-Gly domain-containing protein.
   
 0.996
DCTN3
Dynactin subunit 3.
    
 0.995
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
    
 0.983
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.982
ITSN2
Intersectin 2.
     
 0.977
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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