STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (352 aa)    
Predicted Functional Partners:
IDI1
Isopentenyl-diphosphate delta isomerase 1.
 
 
 0.984
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 0.983
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.981
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
    
 0.973
RSAD2
Radical S-adenosyl methionine domain containing 2.
     
 0.963
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 0.957
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.956
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.947
Fntb
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
   
 0.946
FNTA
Farnesyltransferase, CAAX box, alpha.
     
 0.938
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.