STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RY1P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. (373 aa)    
Predicted Functional Partners:
RRP15
Ribosomal RNA processing 15 homolog.
   
 
 0.968
RSL1D1
Ribosomal L1 domain containing 1.
   
   0.959
SURF6
Surfeit 6.
   
 
 0.956
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 
 0.951
DDX56
DEAD-box helicase 56.
   
   0.932
RPF1
Ribosome production factor 1 homolog.
   
 
 0.932
RBM28
RNA binding motif protein 28.
   
   0.930
DDX27
DEAD-box helicase 27; Belongs to the DEAD box helicase family.
   
   0.929
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.926
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
   
 
 0.926
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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