STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCKAP1NCK associated protein 1. (1140 aa)    
Predicted Functional Partners:
WASF1
WASP family member 1.
    
 0.999
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.999
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.999
ABI1
Abl interactor 1.
    
 0.997
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.996
ABI2
Abl interactor 2.
    
 0.987
WASF2
WASP family member 2.
    
 0.987
RAC2
Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).
   
 0.972
WASF3
WASP family member 3.
    
 0.967
Abi3
Abi_HHR domain-containing protein.
   
 0.964
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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