node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKAP9 | KCNE1 | ENSCPOP00000004367 | ENSCPOP00000023836 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | 0.724 |
AKAP9 | KCNE2 | ENSCPOP00000004367 | ENSCPOP00000022397 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] | 0.825 |
AKAP9 | KCNE3 | ENSCPOP00000004367 | ENSCPOP00000022787 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily E regulatory subunit 3. | 0.744 |
AKAP9 | KCNQ1 | ENSCPOP00000004367 | ENSCPOP00000015076 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] | 0.941 |
AKAP9 | KCNQ2 | ENSCPOP00000004367 | ENSCPOP00000025733 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. | 0.623 |
AKAP9 | KCNQ3 | ENSCPOP00000004367 | ENSCPOP00000008115 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. | 0.623 |
AKAP9 | KCNQ4 | ENSCPOP00000004367 | ENSCPOP00000004475 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. | 0.623 |
AKAP9 | KCNQ5 | ENSCPOP00000004367 | ENSCPOP00000000106 | A-kinase anchoring protein 9. | Potassium voltage-gated channel subfamily Q member 5. | 0.623 |
AKAP9 | Kcnj2 | ENSCPOP00000004367 | ENSCPOP00000031029 | A-kinase anchoring protein 9. | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] | 0.421 |
FAU | KCNQ1 | ENSCPOP00000013255 | ENSCPOP00000015076 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] | 0.969 |
FAU | KCNQ2 | ENSCPOP00000013255 | ENSCPOP00000025733 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. | 0.969 |
FAU | KCNQ3 | ENSCPOP00000013255 | ENSCPOP00000008115 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. | 0.969 |
FAU | KCNQ4 | ENSCPOP00000013255 | ENSCPOP00000004475 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. | 0.969 |
FAU | KCNQ5 | ENSCPOP00000013255 | ENSCPOP00000000106 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Potassium voltage-gated channel subfamily Q member 5. | 0.969 |
KCNE1 | AKAP9 | ENSCPOP00000023836 | ENSCPOP00000004367 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | A-kinase anchoring protein 9. | 0.724 |
KCNE1 | KCNE3 | ENSCPOP00000023836 | ENSCPOP00000022787 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | Potassium voltage-gated channel subfamily E regulatory subunit 3. | 0.745 |
KCNE1 | KCNQ1 | ENSCPOP00000023836 | ENSCPOP00000015076 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] | 0.998 |
KCNE1 | KCNQ2 | ENSCPOP00000023836 | ENSCPOP00000025733 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. | 0.854 |
KCNE1 | KCNQ3 | ENSCPOP00000023836 | ENSCPOP00000008115 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. | 0.850 |
KCNE1 | KCNQ4 | ENSCPOP00000023836 | ENSCPOP00000004475 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] | Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. | 0.867 |