STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CryaaAlpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. (196 aa)    
Predicted Functional Partners:
CRYAB
AlphaB-crystallin; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
    
0.982
CRYBA1
Beta A3-crystallin; Belongs to the beta/gamma-crystallin family.
   
 
 0.948
CRYBB2
BetaB2-crystallin; Belongs to the beta/gamma-crystallin family.
   
 
 0.916
HSPB1
Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.
   
0.871
HSPB6
Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family.
  
0.861
CRYBA2
BetaA2-crystallin; Belongs to the beta/gamma-crystallin family.
   
  
 0.852
CRYGS
GammaS-crystallin; Belongs to the beta/gamma-crystallin family.
   
 
 0.797
HSPB9
Heat shock protein family B (small) member 9; Belongs to the small heat shock protein (HSP20) family.
     
0.764
BAG3
BCL2 associated athanogene 3.
    
 
 0.715
CRYGA
GammaA-crystallin; Belongs to the beta/gamma-crystallin family.
   
 
 0.710
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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