STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F9Coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. (472 aa)    
Predicted Functional Partners:
H0UTW7_CAVPO
SERPIN domain-containing protein; Belongs to the serpin family.
  
 0.989
ENSCPOP00000023625
Uncharacterized protein.
  
 0.989
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
    
 0.946
F11
Coagulation factor XI; Belongs to the peptidase S1 family.
  
0.943
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.940
F10
Coagulation factor X.
  
 
0.931
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
  
0.900
XXYLT1
Xyloside xylosyltransferase 1.
    
   0.881
GGCX
Gamma-glutamyl carboxylase.
    
 0.836
F7
Coagulation factor VII.
  
 
0.832
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.