NLGN1 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NLGN1

Neuroligin 1. (843 aa)

Predicted Functional Partners:

NRXN3

0.977

NRXN2

0.973

ENSCPOP00000027747

0.973

H0VSR6_CAVPO

0.941

DLG4

0.935

NLGN3

0.863

H0W504_CAVPO

0.860

LOC100726574

0.860

SHANK3

0.839

MDGA1

0.809

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLG4	ENSCPOP00000027747	ENSCPOP00000020709	ENSCPOP00000027747	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	LAM_G_DOMAIN domain-containing protein.	0.799
DLG4	H0VSR6_CAVPO	ENSCPOP00000020709	ENSCPOP00000013683	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.681
DLG4	H0W504_CAVPO	ENSCPOP00000020709	ENSCPOP00000018055	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.619
DLG4	LOC100726574	ENSCPOP00000020709	ENSCPOP00000024656	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	LAM_G_DOMAIN domain-containing protein.	0.619
DLG4	NLGN1	ENSCPOP00000020709	ENSCPOP00000016648	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Neuroligin 1.	0.935
DLG4	NLGN3	ENSCPOP00000020709	ENSCPOP00000022872	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Neuroligin 3.	0.869
DLG4	NRXN2	ENSCPOP00000020709	ENSCPOP00000000693	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Neurexin 2.	0.806
DLG4	NRXN3	ENSCPOP00000020709	ENSCPOP00000032858	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Neurexin 3.	0.790
DLG4	SHANK3	ENSCPOP00000020709	ENSCPOP00000015371	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.886
ENSCPOP00000027747	DLG4	ENSCPOP00000027747	ENSCPOP00000020709	LAM_G_DOMAIN domain-containing protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.799
ENSCPOP00000027747	H0VSR6_CAVPO	ENSCPOP00000027747	ENSCPOP00000013683	LAM_G_DOMAIN domain-containing protein.	Uncharacterized protein.	0.905
ENSCPOP00000027747	H0W504_CAVPO	ENSCPOP00000027747	ENSCPOP00000018055	LAM_G_DOMAIN domain-containing protein.	Uncharacterized protein.	0.899
ENSCPOP00000027747	LOC100726574	ENSCPOP00000027747	ENSCPOP00000024656	LAM_G_DOMAIN domain-containing protein.	LAM_G_DOMAIN domain-containing protein.	0.900
ENSCPOP00000027747	NLGN1	ENSCPOP00000027747	ENSCPOP00000016648	LAM_G_DOMAIN domain-containing protein.	Neuroligin 1.	0.973
ENSCPOP00000027747	NLGN3	ENSCPOP00000027747	ENSCPOP00000022872	LAM_G_DOMAIN domain-containing protein.	Neuroligin 3.	0.953
ENSCPOP00000027747	NRXN2	ENSCPOP00000027747	ENSCPOP00000000693	LAM_G_DOMAIN domain-containing protein.	Neurexin 2.	0.796
ENSCPOP00000027747	NRXN3	ENSCPOP00000027747	ENSCPOP00000032858	LAM_G_DOMAIN domain-containing protein.	Neurexin 3.	0.724
ENSCPOP00000027747	SHANK3	ENSCPOP00000027747	ENSCPOP00000015371	LAM_G_DOMAIN domain-containing protein.	SH3 and multiple ankyrin repeat domains 3.	0.807
H0VSR6_CAVPO	DLG4	ENSCPOP00000013683	ENSCPOP00000020709	Uncharacterized protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.681
H0VSR6_CAVPO	ENSCPOP00000027747	ENSCPOP00000013683	ENSCPOP00000027747	Uncharacterized protein.	LAM_G_DOMAIN domain-containing protein.	0.905