STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (338 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.938
ITSN1
Intersectin 1.
    
 0.886
NOS1AP
Nitric oxide synthase 1 adaptor protein.
    
 0.826
DOCK4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
    
 0.812
MET
MET proto-oncogene, receptor tyrosine kinase.
  
 0.804
MST1R
Macrophage stimulating 1 receptor.
  
 0.804
SHANK3
SH3 and multiple ankyrin repeat domains 3.
   
 0.793
SHANK1
SH3 and multiple ankyrin repeat domains 1.
   
 0.793
KALRN
Kalirin RhoGEF kinase.
   
 0.738
TRIO
Trio Rho guanine nucleotide exchange factor.
   
 0.738
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.